Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.4
USERS' SCORE
Good
Based on 9 Reviews
8.3
Supplement Facts
Serving Size: 2 Softgels
Amount Per Serving
%DV
Calories
10
Total Fat
1 g
1%**
Vitamin E (as Natural d-alpha Tocopherol)
300 mg
2000%
Total tocopherols
600 mg
†
Gamma-Tocopherol
200 mg
†
Mixed Palm Tocotrienol Complex (Tocomin®)
10 mg
†
Top Medical Research Studies
9
We investigated whether vitamin E supplementation affects the risk of blood clots, specifically venous thromboembolism (VTE), in women. The Women's Health Study involved nearly 40,000 women who received either vitamin E or a placebo over more than ten years.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Read More
9
We explored how vitamin E affects blood clot breakdown in patients suffering from coronary spastic angina. In a well-structured study, 40 participants were split into groups receiving either vitamin E or a placebo over a month.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
Read More
8
We explored how inducing heme oxygenase-1 (HO-1) could impact blood clot formation in a mouse model. Through a series of tests, we observed that mice treated with a HO-1 inducer showed a significant delay in thrombus formation.
This effect was linked to the production of bilirubin and carbon monoxide, which have protective roles in the bloodstream. Interestingly, when we used a vitamin E analogue, it almost entirely restored this delay in clotting. Overall, these findings suggest that enhancing HO-1 activity may offer a promising approach to prevent undesirable blood clots.
This effect was linked to the production of bilirubin and carbon monoxide, which have protective roles in the bloodstream. Interestingly, when we used a vitamin E analogue, it almost entirely restored this delay in clotting. Overall, these findings suggest that enhancing HO-1 activity may offer a promising approach to prevent undesirable blood clots.
Read More
Most Useful Reviews
9
Prevents blood clots
7 people found this helpful
Vitamin E influences blood clotting by aiding in the prevention of blood clots, enhancing the elasticity of blood vessels, and slowing the formation of cholesterol plaques. This vitamin is crucial for the reproductive system. I recommend taking one capsule every 2-3 days for optimal absorption, especially alongside vitamin A or folic acid for skin, hair, and nails.
Read More
9
Supports blood circulation
5 people found this helpful
I adore Vitamin E! Its primary role is as an antioxidant, crucial for brain health as it inhibits the oxidation of unsaturated fatty acids. It strengthens blood vessel walls, prevents blood clots, maintains cholesterol levels, and enhances skin health by promoting regeneration. My husband and I have seen improvements in our cholesterol and skin, feeling sharper mentally as well.
Read More
9
Boosts muscle strength
3 people found this helpful
The natural tocopherol Vitamin E safeguards cell membranes from free radicals and is vital for brain health. It reinforces blood vessel walls, prevents blood clots, maintains normal cholesterol, and boosts endurance during physical activities. Additionally, it improves hair and skin by aiding in the regeneration of damaged areas. Excellent to combine with vitamin C.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.4
- All Researches
9
Our exploration focused on how tocotrienols, a form of vitamin E, influence blood clotting, especially in the context of risk factors like stroke. Using a canine model, we assessed the effects of tocotrienols on platelet aggregation and thrombus formation.
The findings revealed that tocotrienols significantly inhibited both platelet thrombus formation and collagen-induced platelet aggregation. We noticed that tocotrienols could be converted to tocopherols, which might add to their effectiveness. Overall, these results suggest tocotrienols could offer a therapeutic advantage in preventing serious cardiovascular events.
The findings revealed that tocotrienols significantly inhibited both platelet thrombus formation and collagen-induced platelet aggregation. We noticed that tocotrienols could be converted to tocopherols, which might add to their effectiveness. Overall, these results suggest tocotrienols could offer a therapeutic advantage in preventing serious cardiovascular events.
Read More
9
We investigated whether vitamin E supplementation affects the risk of blood clots, specifically venous thromboembolism (VTE), in women. The Women's Health Study involved nearly 40,000 women who received either vitamin E or a placebo over more than ten years.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Read More
9
We explored the effects of vitamin E and sesamin on blood pressure and blood clot formation using young rats prone to stroke. The rats were divided into four groups: a control group, a vitamin E group, a sesamin group, and a combination group for five weeks.
Notably, the rats receiving vitamin E and sesamin showed lower blood pressure and thrombotic tendencies compared to the control group. However, while there was some reduction in clot formation, it was not substantial enough to conclude a significant clinical benefit.
Thus, we observed that while vitamin E and sesamin may have some protective effects, their impact on blood clot prevention is not definitively established.
Notably, the rats receiving vitamin E and sesamin showed lower blood pressure and thrombotic tendencies compared to the control group. However, while there was some reduction in clot formation, it was not substantial enough to conclude a significant clinical benefit.
Thus, we observed that while vitamin E and sesamin may have some protective effects, their impact on blood clot prevention is not definitively established.
Read More
9
We explored how vitamin E affects blood clot breakdown in patients suffering from coronary spastic angina. In a well-structured study, 40 participants were split into groups receiving either vitamin E or a placebo over a month.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
Read More
8
We explored how inducing heme oxygenase-1 (HO-1) could impact blood clot formation in a mouse model. Through a series of tests, we observed that mice treated with a HO-1 inducer showed a significant delay in thrombus formation.
This effect was linked to the production of bilirubin and carbon monoxide, which have protective roles in the bloodstream. Interestingly, when we used a vitamin E analogue, it almost entirely restored this delay in clotting. Overall, these findings suggest that enhancing HO-1 activity may offer a promising approach to prevent undesirable blood clots.
This effect was linked to the production of bilirubin and carbon monoxide, which have protective roles in the bloodstream. Interestingly, when we used a vitamin E analogue, it almost entirely restored this delay in clotting. Overall, these findings suggest that enhancing HO-1 activity may offer a promising approach to prevent undesirable blood clots.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Prevents blood clots
7 people found this helpful
Vitamin E influences blood clotting by aiding in the prevention of blood clots, enhancing the elasticity of blood vessels, and slowing the formation of cholesterol plaques. This vitamin is crucial for the reproductive system. I recommend taking one capsule every 2-3 days for optimal absorption, especially alongside vitamin A or folic acid for skin, hair, and nails.
Read More
9
Supports blood circulation
5 people found this helpful
I adore Vitamin E! Its primary role is as an antioxidant, crucial for brain health as it inhibits the oxidation of unsaturated fatty acids. It strengthens blood vessel walls, prevents blood clots, maintains cholesterol levels, and enhances skin health by promoting regeneration. My husband and I have seen improvements in our cholesterol and skin, feeling sharper mentally as well.
Read More
9
Boosts muscle strength
3 people found this helpful
The natural tocopherol Vitamin E safeguards cell membranes from free radicals and is vital for brain health. It reinforces blood vessel walls, prevents blood clots, maintains normal cholesterol, and boosts endurance during physical activities. Additionally, it improves hair and skin by aiding in the regeneration of damaged areas. Excellent to combine with vitamin C.
Read More
9
Enhances skin nutrition
1 people found this helpful
Vitamin E is immensely beneficial. It nourishes skin and hair, alleviates dryness, and strengthens nails. It affects blood clotting positively, preventing the formation of blood clots and enhances the elasticity of both large and small vessels while slowing the formation of cholesterol plaques.
Read More
7.5
Improved blood flow
7 people found this helpful
I take two tablets after each meal. Since I began this regimen, my high blood pressure has stabilised, and I haven’t had any issues despite my unchanged habits. Overall, I’ve experienced improved blood flow and heightened sensitivity during intimate activities.
Read More
Frequently Asked Questions
7.5
Helped my numbness
4 people found this helpful
I purchased it to enhance blood circulation as my hands were numb. After taking it with Vitamin C for two weeks, I found it effective in alleviating my numbness. I plan to repeat the course once I finish my current supply.
9
Enhances skin nutrition
1 people found this helpful
Vitamin E is immensely beneficial. It nourishes skin and hair, alleviates dryness, and strengthens nails. It affects blood clotting positively, preventing the formation of blood clots and enhances the elasticity of both large and small vessels while slowing the formation of cholesterol plaques.
7.5
Improved blood flow
7 people found this helpful
I take two tablets after each meal. Since I began this regimen, my high blood pressure has stabilised, and I haven’t had any issues despite my unchanged habits. Overall, I’ve experienced improved blood flow and heightened sensitivity during intimate activities.
6
Essential for heart health
2 people found this helpful
This is indispensable, providing significant benefits for the heart and blood circulation while preventing clots. It's a fantastic addition to my health routine, God willing.
9
Supports blood circulation
5 people found this helpful
I adore Vitamin E! Its primary role is as an antioxidant, crucial for brain health as it inhibits the oxidation of unsaturated fatty acids. It strengthens blood vessel walls, prevents blood clots, maintains cholesterol levels, and enhances skin health by promoting regeneration. My husband and I have seen improvements in our cholesterol and skin, feeling sharper mentally as well.
7.5
Benefits reproductive function
Vitamin E has a beneficial effect on reproductive function for both genders and alleviates menopausal symptoms in women. It improves sperm quality in men and acts as a powerful antioxidant, positively influencing the cardiovascular system, particularly blood vessels. I trust this manufacturer completely and am pleased with my results.
9
Prevents blood clots
7 people found this helpful
Vitamin E influences blood clotting by aiding in the prevention of blood clots, enhancing the elasticity of blood vessels, and slowing the formation of cholesterol plaques. This vitamin is crucial for the reproductive system. I recommend taking one capsule every 2-3 days for optimal absorption, especially alongside vitamin A or folic acid for skin, hair, and nails.
7.5
Improves cholesterol levels
6 people found this helpful
I take this all-purpose antioxidant for its ability to suppress the oxidation of LDL cholesterol in my blood. Taking it with vitamin C seems to create a beneficial synergy. I’ve noticed improved cholesterol levels thanks to this, although caution is advised to avoid excessive doses.
9
We investigated whether vitamin E supplementation affects the risk of blood clots, specifically venous thromboembolism (VTE), in women. The Women's Health Study involved nearly 40,000 women who received either vitamin E or a placebo over more than ten years.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
Our findings revealed that those taking vitamin E experienced a significant reduction in VTE occurrences compared to the placebo group. Notably, women with a history of VTE or certain genetic factors benefited the most from supplementation.
Overall, vitamin E may play a protective role against blood clots, offering promise for at-risk individuals.
7
We examined how vitamin E influences bleeding risks in patients with nonvalvular atrial fibrillation undergoing anticoagulant therapy. In our retrospective study of 566 patients, higher levels of serum vitamin E were associated with increased bleeding events.
Specifically, those who experienced bleeding had significantly higher vitamin E concentrations compared to those who did not. This suggests that elevated vitamin E may predict a higher risk of hemorrhage in patients taking anticoagulants, prompting the need for further research to clarify this relationship with newer medications.
Specifically, those who experienced bleeding had significantly higher vitamin E concentrations compared to those who did not. This suggests that elevated vitamin E may predict a higher risk of hemorrhage in patients taking anticoagulants, prompting the need for further research to clarify this relationship with newer medications.
9
We explored how vitamin E affects blood clot breakdown in patients suffering from coronary spastic angina. In a well-structured study, 40 participants were split into groups receiving either vitamin E or a placebo over a month.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
We observed that those who took vitamin E experienced significant improvements, with decreased levels of a key clotting factor and a marker for oxidative stress. This suggests that vitamin E may serve as an effective addition to treatments for managing coronary spasms, especially in patients without coronary atherosclerosis.
References
- Jafar Haeri SM, Dashti G, Mardani M, Rashidi B, Nikgoftar Fathi A, et al. Effect of Vitamin E on Apoptosis of the Endothelial Cells of the Carotid Arteries in Hypercholesterolemic Male Rabbits. ARYA Atheroscler. 2023;19:10. doi:10.48305/arya.2022.39175.2824
- Ho JI, Ng EY, Chiew Y, Koay YY, Chuar PF, et al. The effects of vitamin E on non-proliferative diabetic retinopathy in type 2 diabetes mellitus: Are they sustainable with 12 months of therapy. SAGE Open Med. 2022;10:20503121221095324. doi:10.1177/20503121221095324
- Ceran C, Aksam E, Aksam B, Yenidünya S, Suludere Z, et al. Tamoxifen-Related Thrombosis: An Experimental Study in Rat Venous Microvascular Anastomosis Model. Ann Plast Surg. 2017;78:213. doi:10.1097/SAP.0000000000000798
- Pastori D, Carnevale R, Cangemi R, Saliola M, Nocella C, et al. Vitamin E serum levels and bleeding risk in patients receiving oral anticoagulant therapy: a retrospective cohort study. J Am Heart Assoc. 2013;2:e000364. doi:10.1161/JAHA.113.000364
- Sasaki Y, Kobara N, Higashino S, Giddings JC, Yamamoto J. Astaxanthin inhibits thrombosis in cerebral vessels of stroke-prone spontaneously hypertensive rats. Nutr Res. 2011;31:784. doi:10.1016/j.nutres.2011.09.010
- Fahim MA, Nemmar A, Singh S, Hassan MY. Antioxidants alleviate nicotine-induced platelet aggregation in cerebral arterioles of mice in vivo. Physiol Res. 2011;60:695.
- Qureshi AA, Karpen CW, Qureshi N, Papasian CJ, Morrison DC, et al. Tocotrienols-induced inhibition of platelet thrombus formation and platelet aggregation in stenosed canine coronary arteries. Lipids Health Dis. 2011;10:58. doi:10.1186/1476-511X-10-58
- Ristow B. Preoperative use of alpha tocopherol does not increase the risk of hematoma in the face lift patient: a preliminary report. Plast Reconstr Surg. 2009;124:1696. doi:10.1097/PRS.0b013e3181b98a3a
- Ping-Chia L, I-Ju L, Yu-Ching L, Li-Ching C, Wen-Chung C. Substance P scavenger enhances antioxidant defenses and prevents prothrombotic effects on the rat lung after acute exposure to oil smoke. J Biomed Sci. 2009;16:58. doi:10.1186/1423-0127-16-58
- Glynn RJ, Ridker PM, Goldhaber SZ, Zee RY, Buring JE. Effects of random allocation to vitamin E supplementation on the occurrence of venous thromboembolism: report from the Women's Health Study. Circulation. 2007;116:1497.
- Singh I, Turner AH, Sinclair AJ, Li D, Hawley JA. Effects of gamma-tocopherol supplementation on thrombotic risk factors. Asia Pac J Clin Nutr. 2007;16:422.
- Allman-Farinelli MA, Dawson B. Diet and aging: bearing on thrombosis and hemostasis. Semin Thromb Hemost. 2005;31:111.
- Noguchi T, Ikeda K, Sasaki Y, Yamamoto J, Yamori Y. Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats. Clin Exp Pharmacol Physiol. 2004;31 Suppl 2:S24.
- Miyamoto S, Kawano H, Takazoe K, Soejima H, Sakamoto T, et al. Vitamin E improves fibrinolytic activity in patients with coronary spastic angina. Thromb Res. 2004;113:345.
- Lindenblatt N, Bordel R, Schareck W, Menger MD, Vollmar B. Vascular heme oxygenase-1 induction suppresses microvascular thrombus formation in vivo. Arterioscler Thromb Vasc Biol. 2004;24:601.
